Core for Homeostatic RegulationOrganization Structure
The ultimate goal of the Core for Homeostatic Regulation is elucidating the mechanisms of onset of human diseases and creation of new scientific paradigms. This Core clarifies the regulation of homeostasis in individuals, focusing on the immune system, metabolism and neuro-endocrine and environmental response systems. In addition, the Core for Homeostatic Regulation will validate the disease models established by the Core for Precise Measuring and Modeling, in a multi-tier timeframe from before to after the onset of diseases.


Core for Precise Measuring and ModelingOrganization Structure
The Core for Precise Measuring and Modeling aims to elucidate the mechanisms of human disease onset through collection of multi-tier timeframe data to build a computational and predictive network of the process. From this perspective they will undertake a comparative review of the collected multi-tier timeframe data in experimental animals, and suggest models that will lead to discovery of mechanisms of disease onset in humans.


Core for Genomic MedicineOrganization Structure
The Core for Genomic Medicine aims to be at the forefront of personalized medicine. This Core will construct a research infrastructure to define variations in the human genome, undertake comprehensive genomic analysis to elucidate the pathogenesis and prognosis of cancer, cardiovascular diseases and diabetes, analyze drug responsiveness by combining genomic information and various environmental factors, and develop technologies for clinical translational research.
  • Yukihide Momozawa

    Yukihide Momozawa

    Laboratory for Genotyping Development

  • Hidewaki Nakagawa

    Hidewaki Nakagawa

    Laboratory for Genome Sequencing Analysis

  • Yoichiro Kamatani

    Yoichiro Kamatani

    Laboratory for Statistical Analysis

  • Taisei Mushiroda

    Taisei Mushiroda

    Laboratory for Pharmacogenomics

  • Taisei Mushiroda

    Taisei Mushiroda

    Laboratory for International Alliance on Genomic Research

  • Kaoru Ito

    Kaoru Ito

    Laboratory for Cardiovascular Diseases

  • Kazuhiko Yamamoto

    Kazuhiko Yamamoto

    Laboratory for Autoimmune Diseases

  • Kazuaki Chayama

    Kazuaki Chayama

    Laboratory for Digestive Diseases

  • Shiro Ikegawa

    Shiro Ikegawa

    Laboratory for Bone and Joint Diseases

  • Momoko Horikoshi

    Momoko Horikoshi

    Laboratory for Endocrinology, Metabolism and Kidney Diseases

  • Mayumi Tamari

    Mayumi Tamari

    Laboratory for Respiratory and Allergic Diseases


Program for Medical InnovationsOrganization Structure
The Program for Medical Innovations targets research aimed at medical application. They will implement the development of therapies for hay fever, food allergies, novel cancer treatment, and regenerative medicine for the immune system using iPS technologies.


  • Tomokatsu Ikawa

    Tomokatsu Ikawa

    YCI Laboratory for Immune Regeneration

  • Toshimori Kitami

    Toshimori Kitami

    YCI Laboratory for Cellular Bioenergetic Network

  • Katsuyuki YUGI

    Katsuyuki Yugi

    YCI Laboratory for Trans-omics

  • Hideyuki YOSHIDA

    Hideyuki Yoshida

    YCI Laboratory for Immunological Transcriptomics

  • Yibo

    Yibo Wu

    YCI Laboratory for Next-Generation Proteomics