Laboratory for Cellular Function Conversion Technology


Team Leader
Harukazu SUZUKI  Ph.D.

1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045[at]

Research Area

Gene expression is regulated by complicated association between transcriptional regulatory network and epigenome landscape such as DNA methylation. We aim at understanding of life phenomena and its disorder, development of novel technologies, and cellular function conversion toward therapy of disease. For this purpose, we proceed various research, such as DNA demethylation-promoting transcription factors and their role, mechanism of disease onset induced by abnormality of DNA methylation regulatory factors, epithelial-to-mesenchymal transition (EMT) process and its related disease, and mechanism of germ cell differentiation.




2018/01/02 Explore the mystery of DNA methylation switch
2017/03/02 Improved gene expression atlas shows that many human long non-coding RNAs may actually be functional
2015/02/13 FANTOM5 project discovers general rules governing how cells change
2014/06/24 Pushing cells towards a higher pluripotency state
2014/03/27 FANTOM5 releases atlas of human gene expression
2013/10/03 Advanced gene expression analysis to facilitate drug development