Our challenge
AMED Moonshot Research and Development Program: The research and development towards “The society with zero-cancer” through the US-Japan collaboration
Project Outline
Project Name:
A world of zero cancer risk created by rejuvenation using cell lineage conversion
Project Overview:
Chronic inflammation, which causes aging and cancer, can be a “double-edged sword” because it has the potential to cause “cell lineage conversion” such as cell rejuvenation. By applying the mechanism of the reprograming in the cells of regenerative medicine, we will develop a technology to “reverse cancer tissues to normal tissues” via cell lineage conversion. Our interdisciplinary approach involves a multi-racial, large-scale clinical studies based on the Japan/US cooperation.
Members
Project Manager (Principal Investigator):
Haruhiko Koseki (Deputy Director, RIKEN Center for Integrative Medical Sciences)
Co-Principal Investigators:
Eiji Hara (Professor, Research Institute for Microbial Diseases, Osaka University)
Yasuhiro Yamada (Professor, Graduate School of Medicine, The University of Tokyo)
Yukinori Okada (Team Leader, RIKEN Center for Integrative Medical Sciences)
Atsushi Kaneda (Professor, Graduate School of Medicine, Chiba University)
Atsushi Shibata (Professor, Keio University Faculty of Pharmacy)
Masumi Abe (Senior Principal Researcher, Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology)
Sumitaka Hasegawa (Director, Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology)
US Partnership Researcher:
Fumito Ito (Associate Professor of Surgery, Norris Comprehensive Cancer Center, University of Southern California)
Achievements
In Preparation
Links
Moonshot Research and Development Program, Cabinet Office, Government of Japan
https://www8.cao.go.jp/cstp/english/moonshot/top.html