Development of a synthetic lymphoid tissue that has immunological function

December 10, 2004 PRESS RELEASE

Dr. Takeshi Watanabe (unit leader) and Dr. Sachiko Suematsu at the Research Unit for Immune Surveillance have developed a synthetic lymphoid tissue–like organoid in mice for the first time in the world.
Synthetic lymphoid tissues have been developed around the world. However, none have succeeded in showing organized tissue structure and strong immunological function in vivo.
The generation of a synthetic lymphoid tissue–like organoid in mice represents a major milestone. It not only contributes a new method in immunology research, but will also have applications in the near future as an effective medical device in the treatment of severe infection, immune deficiency and various types of cancer.
The research results were published in the December issue of the U.S. science journal Nature Biotechnology.