Karolinska Institutet - RIKEN Joint International Doctoral Course 2020 "Bioinformatics analysis of gene regulation in omics data and its applications to medical problems"

March 5th (Thu) - 11th (Wed), 2020

 [DATE and TIME]
 March 5th - 11th, 2020, 9:00 - 18:00
 (with preparation time from Feb 27th to Mar 4th)

 Karolinska Institute, Stockholm, Sweden
 Feb 27th ‒ Mar 4th: distance learning and preparation by participants
 in their free time or in their own lab.
 Mar 5th ‒ 11th: Lectures at Karolinska Institutet.

 Presence at lecture site at Karolinska Institutet is required from Mar 5th to March 11th only. No classes on weekend.

A joint international doctoral course on the subject "Bioinformatics analysis of gene regulation in omics data and its applications to medical problems" between the RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan, and the Karolinska Institutet Department of Cell and Molecular Biology, Sweden, will be held from March 5th to March 11th, 2020, at the Karolinska Institutet, Stockholm, Sweden.

Its main purpose is to give doctoral students the possibility to learn about molecular biology from cutting edge researchers from leading international research institutes. Doctoral students in medical, biological, or biology-related areas currently studying in graduate schools either in Sweden or Japan can participate. Students from Japanese universities can apply for participation now. The course will be held in an international environment with English as the course language.

Applicants are screened and accepted based on suitability and motivation statement. Participants who successfully pass the course examination will receive a certificate of completion. No tuition is required.

Deadline for application for students from Japanese universities is January 24th (Fri), 2020.
For details and inquiries, please contact ki_riken_course2020■■->@)

No tuition fee. The course does not cover travel expenses, daily expenses or accommodation fees.

Lectures about principles of gene regulation in non-disease cases and dysregulation in diseases at individual locus level as well as at the genome-wide level. Principles of sequencing based genomics technologies and corresponding bioinformatics data analysis.

Concrete hands-on bioinformatics data analysis by the students of selected published projects.

After the completed course, the participants will be able to understand the principles and perform basic bioinformatics analysis of genomic sequencing data. The participants will be able to plan experimental designs and to critically evaluate the appropriateness of the different sequencing based omics methods and technologies for genome-wide gene regulation studies. The statistical language R will be used for the hands-on practical. It is recommended that participants have previous experiences with R.


Dr. Erik Arner (RIKEN Center for Integrative Medical Sciences)
Dr. Piero Carninci (RIKEN Center for Integrative Medical Sciences)
Dr. Carsten Daub (Karolinska Institutet/RIKEN Center for Integrative Medical Sciences)
Dr. Bogumil Kaczkowski (RIKEN Center for Integrative Medical Sciences)
Dr. John F. Ouyang (Duke-NUS Medical School)
Dr. Jordan Ramilowski (RIKEN Center for Integrative Medical Sciences)
Dr. David van Bruggen (Karolinska Institutet)
Dr. Katsuyuki Yugi (RIKEN Center for Integrative Medical Sciences)


The course consists of lectures, discussions and seminars. The discussions and seminars are compulsory.
Absence from compulsory parts is compensated according to the instructions from the course leader.

The students will be examined for knowledge and skills, individually based on their active participation in discussions and group-wise for their seminar presentations.

The students are examined for both group-wise and individual presentations in English. The students will work in small groups of 3-5 students. Each group will receive a scientific question related to the course topic on the first day of the course. Students are welcome to propose such a question for their own group. The content has to be related to the course topic. The scientific question will be answered and discussed by the students on the last day of the course during the course evaluation. Each group will be asked to make an oral presentation of the results and each student will present part of the results. The course lecturers will evaluate the performance of each of the students individually. Based on each student's performance during the examination, it will be determined if the student passes the examination or not.

Students who successfully pass the examination will receive official certificates of completion from the Karolinska Institutet.

Special requirements for certificates from the student's university can be considered. Please contact the course administrator before the course if any such requirements exist.


  • Dr. Carsten O. Daub (Karolinska Institutet/RIKEN Center for Integrative Medical Sciences)
  • Dr. Piero Carninci (RIKEN Center for Integrative Medical Sciences)

Eligible applicants
Doctoral students (medical sciences, biology or related fields) currently enrolled in universities in Japan. Doctoral students enrolled at universities outside Japan but working in Japanese research institutes can apply and are asked to clarify the details of their multiple affiliations in the application (What is the main location of their workplace? What is the nature of the association with the Japanese institute? Etc.).

The screening process for students from Swedish universities is already completed.

Number of participants and screening procedures
The maximum number of participants from Japanese universities will be up to 10. Participants will be selected after screening of the application materials by course directors and researchers involved in the course organization and teaching. The most important evaluation criterion is the statement of motivation for attendance. Please explain why you are interested in participating, how the course relates to your current research and how your work will benefit from the course.

Apply for the course using the KI Course_Application Form ( The application deadline is Jan 24th (Fri), 2020.

For details and inquiries, please contact ki_riken_course2020■■ -> @)

Application documents
Fill in the web application form
- Research topic summary (max. 200 words, use the web form)
- Statement of motivation (use the web form)
- Signed letter of support from your supervisor
(format is free, attach to the web application form)

Please understand that we expect the accepted applicants to attend the course. Therefore, we are asking the applicants to provide a letter of support signed by their supervisor.

For further questions regarding application procedures,

please contact ki_riken_course2020■ (■ -> @) or fax to +81-(0)45-503-9562. Notification emails to all applicants will be sent at the end of January 2020.

Applicants should book their accommodations by themselves.
Hotel information in Stockholm with good access to the Karolinska Institutet:

Elite Hotel Carolina Tower - 4 star hotel. 500m walking distance to KI.

Wasa Park Hotel - Guesthouse with lower prices. 1,2 km walking distance to KI.

Stockholm Hostel - Recommended hostel with choice of single rooms. 1,4 km walking distance from KI.

For other hostel alternatives:

KI-RIKEN Joint International Doctoral Course 2020 Secretariat
RIKEN Center for Integrative Medical Sciences, RIKEN Yokohama Institute
1-7-22, Suehiro-cho, Tsurumi-ku, Yokohama, 230-0045 JAPAN
Tel: +81-(0)45-503-9612   Fax: +81-(0)45-503-9562
General inquiries: ki_riken_course2020■■ -> @)
(Please indicate in the Email subject line that your query is about KI-RIKEN Joint International Doctoral Course 2020)