93 239 Takahashi N, Kikuchi H, Usui A, Furusho T, Fujimaru T, Fujiki T, Yanagi T, Matsuura Y, Asano K, Yamamoto K, Ando F, Susa K, Mandai S, Mori T, Rai T, Uchida S, Arita M, Sohara E. Deletion of Alox15 improves kidney dysfunction and inhibits fibrosis by increased PGD2 in the kidney. Clin Exp Nephrol 25, 445-455 (2021) 240 Takahashi T, Heaton SM, Parrish NF. Mammalian antiviral systems directed by small RNA. PLoS Pathog 17, e1010091 (2021) 241 Takamatsu K, Tanaka N, Hakozaki K, Takahashi R, Teranishi Y, Murakami T, Kufukihara R, Niwa N, Mikami S, Shinojima T, Sasaki T, Sato Y, Kume H, Ogawa S, Kakimi K, Kamatani T, Miya F, Tsunoda T, Aimono E, Nishihara H, Sawada K, Imamura T, Mizuno R, Oya M. Profiling the inhibitory receptors LAG-3, TIM-3, and TIGIT in renal cell carcinoma reveals malignancy. Nat Commun 12, 5547 (2021) 242 Takaoka A, Ishikawa T, Okazaki S, Watanabe S, Miya F, Tsunoda T, Kikuchi A, Yamauchi S, Matsuyama T, Tokunaga M, Uetake H, Kinugasa Y. ELF3 Overexpression as Prognostic Biomarker for Recurrence of Stage II Colorectal Cancer. In Vivo 35, 191-201 (2021) 243 Takeuchi T, Miyauchi E, Kanaya T, Kato T, Nakanishi Y, Watanabe T, Kitami T, Taida T, Sasaki T, Negishi H, Shimamoto S, Matsuyama A, Kimura I, Williams IR, Ohara O, Ohno H. Acetate differentially regulates IgA reactivity to commensal bacteria. Nature 595, 560-564 (2021) 244 Takeuchi T, Ohno H. Reciprocal regulation of IgA and the gut microbiota: a key mutu-alism in the intestine. Int Immunol 33, 781-786 (2021) 245 Tanaka N, Koido M, Suzuki A, Otomo N, Suetsugu H, Kochi Y, Tomizuka K, Momozawa Y, Kamatani Y; Biobank Japan Project, Ikegawa S, Yamamoto K, Terao C. Eight novel susceptibility loci and putative causal variants in atopic dermatitis. J Allergy Clin Im-munol 148, 1293-1306 (2021) 246 Tanigawa T, Watanabe T, Higashimori A, Shimada S, Kitamura H, Kuzumoto T, Nadatani Y, Otani, Fukunaga S, Hosomi S, Fumio Tanaka, Kamata N, Nagami Y, Taira K, Shiba M, Suda W, Hattori M, Fujiwara Y. Rebamipide ameliorates indomethacin-induced small intestinal damage and proton pump inhibitor-induced exacerbation of this damage by modulation of small intestinal microbiota. PLoS One 16, e0245995 (2021) 247 Terao C, Ota M, Iwasaki T, Shirokawa M, Kawaguchi S, Kuriyama K, Kawaguchi T, Ko-dama Y, Yamaguchi I, Uchida K, Higasa K, Yamamoto M, Kubota K, Yazumi S, Hirano K, Masaki Y, Maguchi H, Origuchi T, Matsui S, Nakazawa T, Shiomi H, Kamisawa T, Hasebe O, Iwasaki E, Inui K, Tanaka Y, Oshima K, Akamizu T, Nakamura S, Nakamura S, Saeki T, Umehara H, Shimosegawa T, Mizuno N, Kawano M, Azumi A, Takahashi H, Mimori T, Kamatani Y, Okazaki K, Chiba T, Kawa S, Matsuda F, the Japanese IgG4-Related Disease Working Consortium o. IgG4-related disease in the Japanese population: a genome-wide association study. Lancet Rheumatol 1, e14-e22 (2021) 248 Teratani T, Mikami Y, Nakamoto N, Suzuki T, Harada Y, Okabayashi K, Hagihara Y, Taniki N, Kohno K, Shibata S, Miyamoto K, Ishigame H, Chu P, Sujino T, Suda W, Hattori M, Matsui M, Okada T, Okano H, Inoue M, Yada T, Kitagawa Y, Yoshimura A, Tanida M, Tsuda M, Iwasaki Y, Kanai T. The liver-brain-gut neural arc maintains the T reg cell niche in the gut. Nature 585, 591-596 (2021) 249 Tokuhiro T, Ishikawa A, Sato H, Takita S, Yoshikawa A, Anzai R, Sato S, Aoyagi R, Arita M, Shibuya T, Aratani Y, Shimizu S, Tanaka M, Yotsumoto S. Oxidized Phospholipids and Neutrophil Elastase Coordinately Play Critical Roles in NET Formation. Front Cell Dev Biol 9, 718586 (2021) 250 Tomofuji Y, Kishikawa T, Maeda Y, Ogawa K, Nii T, Okuno T, Oguro-Igashira E, Kinoshita M, Yamamoto K, Sonehara K, Yagita M, Hosokawa A, Motooka D, Matsumoto Y, Mat-suoka H, Yoshimura M, Ohshima S, Nakamura S, Inohara H, Mochizuki H, Takeda K, Kumanogoh A, Okada Y. Whole gut virome analysis of 476 Japanese revealed a link between phage and autoimmune disease. Ann Rheum Dis 81, 278-288 (2021) 251 Toyama N, Ekuni D, Matsui D, Koyama T, Nakatochi M, Momozawa Y, Kubo M, Morita M. Comprehensive Analysis of Risk Factors for Periodontitis Focusing on the Saliva Microbiome and Polymorphism. Int J Environ Res Public Health 18, 6430 (2021) 252 Trier AM, Mack MR, Fredman A, Tamari M, Ver Heul AM, Zhao Y, Guo CJ, Avraham O, Ford ZK, Oetjen LK, Feng J, Dehner C, Coble D, Badic A, Joshita S, Kubo M, Gereau RW 4th, Alexander-Brett J, Cavalli V, Davidson S, Hu H, Liu Q, Kim BS. IL-33 signaling in sensory neurons promotes dry skin itch. J Allergy Clin Immunol, doi: 10.1016/j.jaci.2021.09.014 (Epub 2021) 253 Tsuchiya H, Ota M, Sumitomo S, Ishigaki K, Suzuki A, Sakata T, Tsuchida Y, Inui H, Hirose J, Kochi Y, Kadono Y, Shirahige K, Tanaka S, Yamamoto K, Fujio K. Parsing multiomics landscape of activated synovial fibroblasts highlights drug targets linked to genetic risk of rheumatoid arthritis. Ann Rheum Dis, doi: 10.1136/annrheum-dis-2020-218189 (Epub 2021) 254 Tsuji D, Saito Y, Mushiroda T, Miura M, Hira D, Terada T. Results of a nationwide survey of Japanese pharmacists regarding the application of pharmacogenomic testing in precision medicine. J Clin Pharm Ther 46, 649-657 (2021) 255 Tsuji H, Ohmura K, Jin H, Naito R, Arase N, Kohyama M, Suenaga T, Sakakibara S, Kochi Y, Okada Y, Yamamoto K, Kikutani H, Morinobu A, Mimori T, Arase H. Anti-Double-Stranded DNA Antibodies Recognize DNA Presented on HLA Class II Molecules of Systemic Lupus Erythematosus Risk Alleles. Arthritis Rheumatol 74, 105-111 (2021) 256 Uchiyama Y, Yamaguchi D, Iwama K, Miyatake S, Hamanaka K, Tsuchida N, Aoi H, Azuma Y, Itai T, Saida K, Fukuda H, Sekiguchi F, Lei, Ohori S, Sakamoto M, Kato M, Koike T, Takahashi Y, Tanda K, Hyodo Y, Matsumoto N, Honjo RS, Bertola DR, Kim CA, Goto M, Okazaki T, Yamada H, Maegaki Y, Osaka H, Ngu L, Siew CG, Teik KW, Akasaka M, Doi H, Tanaka F, Goto T, Guo L, Ikegawa S, Haginoya K, Haniffa M, Hiraishi N, Hiraki Y, Ikemoto S, Atsuro Daida A, Hamano S, Okamoto N, Okanishi T, Oyoshi Y, Takeshita E, Suzuki T, Ogawa Y, Handa H, Miyazono Y, Koshimizu E, Fujita A, Takata A, Miyake N, Mizuguchi T. Efficient detection of copy-number variations using exome data: Batch- and sex-based analyses. Hum Mutat 42, 50-65 (2021) 257 Urushiyama D, Ohnishi E, Suda W, Kurakazu M, Kiyoshima C, Hirakawa T, Miyata K, Yotsumoto F, Nabeshima K, Setoue T, Nagamitsu S, Hattori M, Hata K, Miyamoto S. Vaginal microbiome as a tool for prediction of chorioamnionitis in preterm labor: a pilot study. Sci Rep 11, 18971 (2021) 258 Vogelezang S, Bradfield J, Ahluwalia T, Curtin J, Lakka T, Grarup N, Scholz M, van der Most P, Monnereau C, Stergiakouli E, Heiskala A, Horikoshi M, Fedko I, Vilor-Tejedor N, Cousminer D, Standl M, Wang C, Viikari J, Geller F, Íñiguez C, Pitkänen N, Chesi A, Bacelis J, Yengo L, Torrent M, Ntalla I, Helgeland Ø, Selzam S, Vonk J, Zafarmand M, Heude B, Farooqi I, Alyass A, Beaumont R, Have C, Rzehak P, Bilbao J, Schnurr T, Barroso I, Bønnelykke K, Beilin L, Carstensen L, Charles M, Chawes B, Clément K, Closa-Monasterolo R, Custovic A, Eriksson J, Escribano J, Groen-Blokhuis M, Grote V, Gruszfeld D, Hakonarson H, Hansen T, Hattersley A, Hollensted M, Hottenga J, Hyp-pönen E, Johansson S, Joro R, Kähönen M, Karhunen V, Kiess W, Knight B, Koletzko B, Kühnapfel A, Landgraf K, Langhendries J, Lehtimäki T, Leinonen J, Li A, Lindi V, Lowry E, Bustamante M, Medina-Gomez C, Melbye M, Michaelsen K, Morgen C, Mori T, Nielsen T, Niinikoski H, Oldehinkel A, Pahkala K, Panoutsopoulou K, Pedersen O, Pennell C, Power C, Reijneveld S, Rivadeneira F, Simpson A, Sly P, Stokholm J, Teo K, Thiering E, Timpson N, Uitterlinden A, van Beijsterveldt C, van Schaik B, Vaudel M, Verduci E, Vinding R, Vogel M, Zeggini E, Sebert S, Lind M, Brown C, Santa-Marina L, Reischl E, Frithioff-Bøjsøe C, Meyre D, Wheeler E, Ong K, Nohr E, Vrijkotte T, Koppelman G, Plo-min R, Njølstad P, Dedoussis G, Froguel P, Sørensen T, Jacobsson B, Freathy R, Zemel B, Raitakari O, Vrijheid M, Feenstra B, Lyytikäinen L, Snieder H, Kirsten H, Holt P, Heinrich J, Widén E, Sunyer J, Boomsma D, Järvelin M, Körner A, Davey Smith G, Holm J, Atalay M, Murray C, Bisgaard H, McCarthy M, Jaddoe V, Grant S, Felix J. Novel loci for child-hood body mass index and shared heritability with adult cardiometabolic traits. PLoS Genet 16, e1008718 (2021) 259 Võsa U, Claringbould A, Westra HJ, Bonder MJ, Deelen P, Zeng B, Kirsten H, Saha A, Kreuzhuber R, Yazar S, Brugge H, Oelen R, de Vries DH, van der Wijst MGP, Kasela S, Pervjakova N, Alves I, Favé MJ, Agbessi M, Christiansen MW, Jansen R, Seppälä I, Tong L, Teumer A, Schramm K, Hemani G, Verlouw J, Yaghootkar H, Sönmez Flitman R, Brown A, Kukushkina V, Kalnapenkis A, Rüeger S, Porcu E, Kronberg J, Kettunen J, Lee B, Zhang F, Qi T, Hernandez JA, Arindrarto W, Beutner F; BIOS Consortium; i2QTL Consortium, Dmitrieva J, Elansary M, Fairfax BP, Georges M, Heijmans BT, Hewitt AW, Kähönen M, Kim Y, Knight JC, Kovacs P, Krohn K, Li S, Loeffler M, Marigorta UM, Mei H, Momozawa Y, Müller-Nurasyid M, Nauck M, Nivard MG, Penninx BWJH, Pritchard JK, Raitakari OT, Rotzschke O, Slagboom EP, Stehouwer CDA, Stumvoll M, Sullivan P, 't Hoen PAC, Thiery J, Tönjes A, van Dongen J, van Iterson M, Veldink JH, Völker U, Warmerdam R, Wijmenga C, Swertz M, Andiappan A, Montgomery GW, Ripatti S, Perola M, Kutalik Z, Dermitzakis E, Bergmann S, Frayling T, van Meurs J, Prokisch H, Ahsan H, Pierce BL, Lehtimäki T, Boomsma DI, Psaty BM, Gharib SA, Awadalla P, Milani L, Ouwehand WH, Downes K, Stegle O, Battle A, Visscher PM, Yang J, Scholz M, Powell J, Gibson G, Esko T, Franke L. Large-scale cis- and trans-eQTL analyses identify thou-sands of genetic loci and polygenic scores that regulate blood gene expression. Nat Genet 53, 1300-1310 (2021) 260 Vuckovic’, Bao E, Akbari P, Lareau C, Mousas A, Jiang T, Chen M, Raffield L, Tardaguila M, Huffman J, Ritchie S, Megy K, Ponstingl H, Penkett C, Albers P, Wigdor E, Sakaue S, Moscati A, Manansala R, Lo K, Qian H, Akiyama M, Bartz T, Ben-Shlomo Y, Beswick A, Bork-Jensen J, Bottinger E, Brody J, van Rooij F, Chitrala K, Wilson P, Choquet H, Danesh J, Di Angelantonio E, Dimou N, Ding J, Elliott P, Esko T, Evans M, Felix S, Floyd J, Broer L, Grarup N, Guo M, Guo Q, Greinacher A, Haessler J, Hansen T, Howson J, Huang W, Jorgenson E, Kacprowski T, Kähönen M, Kamatani Y, Kanai M, Karthikeyan S, Koskeridis F, Lange L, Lehtimäki T, Linneberg A, Liu Y, Lyytikäinen L, Manichaikul A, Matsuda K, Mohlke K, Mononen N, Murakami Y, Nadkarni G, Nikus K, Pankratz N, Pedersen O, Pre-uss M, Psaty B, Raitakari O, Rich S, Rodriguez B, Rosen J, Rotter J, Schubert P, Spracklen C, Surendran P, Tang H, Tardif J, Ghanbari M, Völker U, Völzke H, Watkins N, Weiss S, Cai N, Kundu K, Watt S, Walter K, Zonderman A, Cho K, Li Y, Loos R, Knight J, Georges M, Stegle O, Evangelou E, Okada Y, Roberts D, Inouye M, Johnson A, Auer P, Astle W, Reiner A, Butterworth A, Ouwehand W, Lettre G, Sankaran V, Soranz’ N. The Polygenic and Monogenic Basis of Blood Traits and Diseases. Cell 182, 1214-1231.e11 (2021)
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