YCI Laboratory for Next-Generation Proteomics

Yibo Wu obtained her PhD in Biochemistry and Cell Biology from Chinese Academy of Sciences, where she has developed mass spectrometry methods for phosphoproteomics studies. She applied these methods to investigate how phosphorylation of transcription factors regulate protein expression of their target genes in metabolic pathways. After her PhD, she joined the group of Prof. Ruedi Aebersold at ETH Zurich as a postdoctoral fellow. At ETH Zurich, she focused on understanding how genotype and environment coordinately influence phenotype, through regulation on transcripts, proteins and metabolites. She has developed mass spectrometry methods to acquire highly accurate and reproducible protein quantification data across large number of mice cohorts from a genetic reference population. The multilayered omics approach has enabled validation of several links between genetic traits variants toward transcripts, proteins, metabolites and phenotypes. At IMS, Yibo explores the capacity of next-generation proteomics methods to obtain highly reliable protein quantification data and the use of these data to understand the molecular bases of aging and diseases.



TEL: +81-45-503-7034 (6261/8172)

E-mail: yibo.wu AT riken.jp